A new study shows that common baker's yeast (Saccharomyces cerevisiae) can survive Mars-like conditions, including meteorite shock waves and toxic perchlorate salts found in Martian soil. Phys.org reports: Published in PNAS Nexus, Purusharth I. Rajyaguru and colleagues subjected Saccharomyces cerevisiae, which is a widely used model yeast, to shock waves and perchlorates. The authors chose the yeast in part because it has already been studied in space. When stressed, yeast, humans, and many other organisms form ribonucleoprotein (RNP) condensates, structures made of RNA and proteins that protect RNA and affect the fates of mRNAs. When the stressor passes, the RNP condensates, which include subtypes known as stress granules and P-bodies, disassemble.

The authors simulated Martian shock waves at the High-Intensity Shock Tube for Astrochemistry (HISTA) housed in the Physical Research Laboratory in Ahmedabad, India. Yeast exposed to 5.6 Mach intensity shock waves survived with slowed growth, as did yeast subjected to 100 mM sodium salt of perchlorate (NaClO4) -- a concentration similar to that in Martian soils. Yeast cells also survived exposure to the combined stress of shock waves and perchlorate stress. In both cases, the yeast assembled RNP condensates. Shock waves induced the assembly of stress granules and P-bodies; perchlorate caused yeast to make P-bodies but not stress granules. Mutants incapable of assembling RNP condensates were poor at surviving the Martian stress condition. Transcriptome analysis identified specific RNA transcripts perturbed by Mars-like conditions.

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The Free Software Foundation (FSF) has launched the LibrePhone Project, an initiative to create a fully free and open-source mobile operating system that eliminates proprietary firmware and binary blobs. From the FSF: "Librephone is a new initiative by the FSF with the goal of bringing full freedom to the mobile computing environment. The vast majority of software users around the world use a mobile phone as their primary computing device. After forty years of advocacy for computing freedom, the FSF will now work to bring the right to study, change, share, and modify the programs users depend on in their daily lives to mobile phones.
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Practically, Librephone aims to close the last gaps between existing distributions of the Android operating system and software freedom. The FSF has hired experienced developer Rob Savoye (DejaGNU, Gnash, OpenStreetMap, and more) to lead the technical project. He is currently investigating the state of device firmware and binary blobs in other mobile phone freedom projects, prioritizing the free software work done by the not entirely free software mobile phone operating system LineageOS." The project site can be found here.

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