Traditional business applications will become the mainframes of the 2030s - functioning but obsolete systems replaced by AI agents, predicts Microsoft corporate vice president Charles Lamanna. AI agents featuring generative AI interfaces, goal-oriented processing, and vector databases will supplant today's form-driven, workflow-based enterprise software within five years, said Lamanna, who leads Microsoft's business applications and platforms division.

The executive projects industry patterns for agent-based systems will solidify within 6-18 months. Microsoft MVP Rocky Lhotka called the 2030 timeline "very forward-looking and optimistic," noting that capital-intensive industries cannot readily replace existing infrastructure with virtual agents.

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