Nvidia has confirmed on its forums that the RTX 50 series GPUs no longer support 32-bit PhysX. Tom's Hardware reports: As far as we know, there are no 64-bit games with integrated PhysX technology, thus terminating the tech entirely on RTX 50 series GPUs and newer. RTX 40 series and older will still be able to run 32-bit CUDA applications and thus PhysX, but regardless, the technology is now officially retired, starting with Blackwell. [...]

The only way now to run PhysX on RTX 50 series GPUs (or newer) is to install a secondary RTX 40 series or older graphics card and slave it to PhysX duty in the Nvidia control panel. As far as we are aware, Nvidia has not disabled this sort of functionality. But the writing is on the wall for PhysX, and we doubt there will be any future games that attempt to use the API.

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